Title : Role of extracellular electrolytes in the activation of ribosomal protein S6 kinase by epidermal growth factor, insulin-like growth factor 1, and insulin in ZR-75-1 cells.

Pub. Date : 1988 Feb

PMID : 3276717






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In contrast to the responses to EGF, insulin- and IGF1-activation of S6 kinase was enhanced when glucose was present and depended on the presence of bicarbonate in the medium. Bicarbonates insulin Homo sapiens
2 Furthermore, the mechanism of insulin activation of S6 kinase is distinct from the growth factors by its dependency on extracellular bicarbonate. Bicarbonates insulin Homo sapiens