Title : Factors affecting bone maturation in Chinese girls aged 4-8 years with isolated premature thelarche.

Pub. Date : 2020 Jul 29

PMID : 32727432






4 Functional Relationships(s)
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1 The advanced BA group had significantly higher BMI SDS, serum DHEAS SDS, IGF-1 SDS, androstenedione and fasting insulin and significantly lower sex hormone binding globulin (all p < 0.001). Barium insulin like growth factor 1 Homo sapiens
2 In the multiple linear regression model, serum IGF-1 SDS, BMI SDS and DHEAS SDS were the strongest predictors of advanced BA, accounting for 19.3% of the variance. Barium insulin like growth factor 1 Homo sapiens
3 In the subgroup with normal weight, higher serum IGF-1 SDS (p = 0.009) and DHEAS SDS (p = 0.003) affected BA advancement independent of BMI SDS. Barium insulin like growth factor 1 Homo sapiens
4 Age-specific serum IGF-1 SDS and DHEAS SDS were risk factors for BA advancement independent of BMI. Barium insulin like growth factor 1 Homo sapiens