Pub. Date : 2020 Dec
PMID : 32726518
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Vernodalin induces apoptosis through the activation of ROS/JNK pathway in human colon cancer cells. | vernodalin | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | Small interfering RNA was used to analyze the cascade activation of mitogen-activated protein kinase (MAPK) pathway, c-Jun N-terminal kinase (JNK) in HT-29, and HCT116 cells against vernodalin treatment. | vernodalin | mitogen-activated protein kinase 8 | Homo sapiens |
| 3 | Small interfering RNA was used to analyze the cascade activation of mitogen-activated protein kinase (MAPK) pathway, c-Jun N-terminal kinase (JNK) in HT-29, and HCT116 cells against vernodalin treatment. | vernodalin | mitogen-activated protein kinase 8 | Homo sapiens |
| 4 | Immunoblot analysis on the JNK, ERK, and p38 MAPK pathways showed increased activation due to vernodalin treatment. | vernodalin | mitogen-activated protein kinase 8 | Homo sapiens |
| 5 | It was proven from the JNK and p38 inhibition test that both pathways are significantly activated by vernodalin to induce apoptosis. | vernodalin | mitogen-activated protein kinase 8 | Homo sapiens |