Title : Cytochrome P-450-mediated denitrification of 2-nitropropane in mouse liver microsomes.

Pub. Date : 1986 Sep

PMID : 3271881






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The involvement of cytochrome P-450 (P-450) as the catalyst in 2NP denitrification was revealed by the induction of nitrite-releasing activity following phenobarbital (PB) pretreatment, by a decrease in activity with carbon tetrachloride pretreatment, by the inhibition of the reaction with classical P-450 inhibitors, and by the observation of a type I binding spectrum. Phenobarbital cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus
2 The involvement of cytochrome P-450 (P-450) as the catalyst in 2NP denitrification was revealed by the induction of nitrite-releasing activity following phenobarbital (PB) pretreatment, by a decrease in activity with carbon tetrachloride pretreatment, by the inhibition of the reaction with classical P-450 inhibitors, and by the observation of a type I binding spectrum. Phenobarbital cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus