Title : Flucloxacillin decreases tacrolimus blood trough levels: a single-center retrospective cohort study.

Pub. Date : 2020 Dec

PMID : 32712713






2 Functional Relationships(s)
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1 Several case reports have reported that flucloxacillin appeared to decrease levels of drugs metabolized by CYP3A4 and P-gp. Floxacillin cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 CONCLUSIONS: Flucloxacillin decreases tacrolimus trough levels, possibly through a CYP3A4 and/or P-gp-inducing effect. Floxacillin cytochrome P450 family 3 subfamily A member 4 Homo sapiens