Title : Small molecule therapeutics for COVID-19: repurposing of inhaled furosemide.

Pub. Date : 2020

PMID : 32704455






3 Functional Relationships(s)
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1 Upon treatment with furosemide, LPS-induced production of pro-inflammatory cytokines was reduced, indicating that furosemide suppresses the M1 polarization, including IL-6 and TNF-alpha release. Furosemide interleukin 6 Homo sapiens
2 Upon treatment with furosemide, LPS-induced production of pro-inflammatory cytokines was reduced, indicating that furosemide suppresses the M1 polarization, including IL-6 and TNF-alpha release. Furosemide interleukin 6 Homo sapiens
3 Accordingly, we conclude that furosemide is a reasonably potent inhibitor of IL-6 and TNF-alpha that is also safe, inexpensive and well-studied. Furosemide interleukin 6 Homo sapiens