Title : P450 CYP17A1 Variant with a Disordered Proton Shuttle Assembly Retains Peroxo-Mediated Lyase Efficiency.

Pub. Date : 2020 Dec 15

PMID : 32681807






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Human cytochrome P450 CYP17A1 first catalyzes hydroxylation at the C17 position of either PREG or PROG, and a subsequent C 17 -C 20 bond scission to produce dehydroepiandrosterone ( DHEA) or androstenedione (AD). Androstenedione cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 Human cytochrome P450 CYP17A1 first catalyzes hydroxylation at the C17 position of either PREG or PROG, and a subsequent C 17 -C 20 bond scission to produce dehydroepiandrosterone ( DHEA) or androstenedione (AD). Androstenedione cytochrome P450 family 17 subfamily A member 1 Homo sapiens