Title : Pindolol potentiates the antidepressant effect of venlafaxine by inhibiting 5-HT1A receptor in DRN neurons of mice.

Pub. Date : 2022 Jan

PMID : 32677492






4 Functional Relationships(s)
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1 Pindolol potentiate the antidepressant effect of venlafaxine by inhibiting 5-HT1A receptor in DRN neurons of mice. Pindolol 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus
2 Pindolol may eliminate this inhibition when used in combination with antidepressants.Material and methods: We aimed to determine the effect of pindolol on 5-HT1A receptor response in the DRN neurons, using voltage clamp recordings and prove the potentiation of antidepressant effect of venlafaxine by pindolol through behavior experiments. Pindolol 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus
3 Pindolol may eliminate this inhibition when used in combination with antidepressants.Material and methods: We aimed to determine the effect of pindolol on 5-HT1A receptor response in the DRN neurons, using voltage clamp recordings and prove the potentiation of antidepressant effect of venlafaxine by pindolol through behavior experiments. Pindolol 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus
4 Pindolol may eliminate this inhibition when used in combination with antidepressants.Material and methods: We aimed to determine the effect of pindolol on 5-HT1A receptor response in the DRN neurons, using voltage clamp recordings and prove the potentiation of antidepressant effect of venlafaxine by pindolol through behavior experiments. Pindolol 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus