Title : Differences in Theophylline Clearance Between Patients With Chronic Hepatitis and Those With Liver Cirrhosis.

Pub. Date : 2020 Dec

PMID : 32657910






1 Functional Relationships(s)
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1 The final model of theophylline clearance was as follows: CL/F (L/hr/kg) = 0.0484 x 1.40 x 0.861 x 0.889 x 0.557.Smoking is a well-known factor that markedly enhances CL/F through the induction of CYP1A enzymes, whereas CAM has been reported to inhibit CYP3A4. Theophylline cytochrome P450 family 3 subfamily A member 4 Homo sapiens