Title : Fasudil inhibits the activation of microglia and astrocytes of transgenic Alzheimer's disease mice via the downregulation of TLR4/Myd88/NF-κB pathway.

Pub. Date : 2020 Jun 23

PMID : 32652366






2 Functional Relationships(s)
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1 Fasudil inhibits the activation of microglia and astrocytes of transgenic Alzheimer"s disease mice via the downregulation of TLR4/Myd88/NF-kappaB pathway. fasudil myeloid differentiation primary response gene 88 Mus musculus
2 Our experiments suggest Fasudil exerted these functions by inhibing the expression of TLR4, MyD88, and NF-kappaB, which are key mediators of inflammation. fasudil myeloid differentiation primary response gene 88 Mus musculus