Title : Plasminogen activator inhibitor type 1: cell-specific and differentiation-induced expression and regulation in human cell lines, as determined by enzyme-linked immunosorbent assay.

Pub. Date : 1988 Nov

PMID : 3265112






3 Functional Relationships(s)
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1 We have performed a comparative study of the regulation by glucocorticoids and phorbol 12-myristate 13-acetate (PMA) of the production of type 1 plasminogen activator inhibitor (PAI-1) by 12 human cell lines. Tetradecanoylphorbol Acetate serpin family E member 1 Homo sapiens
2 We have performed a comparative study of the regulation by glucocorticoids and phorbol 12-myristate 13-acetate (PMA) of the production of type 1 plasminogen activator inhibitor (PAI-1) by 12 human cell lines. Tetradecanoylphorbol Acetate serpin family E member 1 Homo sapiens
3 In addition, PMA-induced differentiation of the monocyte cell line U937 and the promyelocytic cell line HL-60 into macrophage-like cells was found to be correlated with an up to 100-fold increase in PAI-1 accumulation. Tetradecanoylphorbol Acetate serpin family E member 1 Homo sapiens