Title : The effect of simvastatin on gene expression of low-density lipoprotein receptor, sterol regulatory element-binding proteins, stearoyl-CoA desaturase 1 mRNA in rat hepatic tissues.

Pub. Date : 2020 Jul 9

PMID : 32643419






2 Functional Relationships(s)
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1 The study aimed to assess the effect of simvastatin on gene expression of LDLR, SREBPs, and SCD1 in rat hepatic tissues fed with high-fat diets (HFD) and its association with some biochemical parameters. Simvastatin low density lipoprotein receptor Rattus norvegicus
2 Treatment of rats with HFD and simvastatin 20 mg/kg, triglyceride and LDL were almost the same as a control group and LDLR expression increased 98% in liver tissue. Simvastatin low density lipoprotein receptor Rattus norvegicus