Title : Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation.

Pub. Date : 2020 Aug 6

PMID : 32640193






1 Functional Relationships(s)
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1 Mutation of the hydroxylation acceptor proline precludes tyrosine autophosphorylation and folding of DYRK1, resulting in a kinase unable to preserve VHL function and lacking glioma suppression activity. Proline von Hippel-Lindau tumor suppressor Homo sapiens