Title : Kinome capture sequencing of high-grade serous ovarian carcinoma reveals novel mutations in the JAK3 gene.

Pub. Date : 2020

PMID : 32639993






2 Functional Relationships(s)
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1 Importantly, p.T1022I JAK3 mutants displayed higher sensitivity to the JAK3-selective inhibitor Tofacitinib compared to controls. tofacitinib Janus kinase 3 Mus musculus
2 Importantly, p.T1022I JAK3 mutants displayed higher sensitivity to the JAK3-selective inhibitor Tofacitinib compared to controls. tofacitinib Janus kinase 3 Mus musculus