Title : Salubrinal in Combination With 4E1RCat Synergistically Impairs Melanoma Development by Disrupting the Protein Synthetic Machinery.

Pub. Date : 2020

PMID : 32637352






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 P5CS is involved in proline biosynthesis and targeting ALDH18A1 has previously been shown to inhibit melanoma development by decreasing intracellular proline levels to increase the phosphorylation of eIF2alpha mediated by GCN2, which then impairs mRNA translation. Proline aldehyde dehydrogenase 18 family member A1 Homo sapiens
2 P5CS is involved in proline biosynthesis and targeting ALDH18A1 has previously been shown to inhibit melanoma development by decreasing intracellular proline levels to increase the phosphorylation of eIF2alpha mediated by GCN2, which then impairs mRNA translation. Proline aldehyde dehydrogenase 18 family member A1 Homo sapiens
3 P5CS is involved in proline biosynthesis and targeting ALDH18A1 has previously been shown to inhibit melanoma development by decreasing intracellular proline levels to increase the phosphorylation of eIF2alpha mediated by GCN2, which then impairs mRNA translation. Proline aldehyde dehydrogenase 18 family member A1 Homo sapiens