Title : Novel Melatonin, Estrogen, and Progesterone Hormone Therapy Demonstrates Anti-Cancer Actions in MCF-7 and MDA-MB-231 Breast Cancer Cells.

Pub. Date : 2020

PMID : 32636633






1 Functional Relationships(s)
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1 For MDA-MB-231 cells, BIX02189 combined with melatonin, estrogen, and progesterone inhibited proliferation and increased pERK1/2 and beta1-INTEGRIN; levels of pERK5 remained low/nearly absent in both breast cancer lines. Progesterone integrin subunit beta 1 Homo sapiens