Pub. Date : 2020 Jul 1
PMID : 32635975
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ribavirin uptake was inhibited by nucleosides such as adenosine and uridine, and by inhibitors of equilibrative nucleoside transporter 1 (ENT1) such as S-(4-nitrobenzyl)-6-thioinosine and dipyridamole in a concentration-dependent manner. | Ribavirin | solute carrier family 29 member 1 (Augustine blood group) | Homo sapiens |
| 2 | Ribavirin uptake was inhibited by nucleosides such as adenosine and uridine, and by inhibitors of equilibrative nucleoside transporter 1 (ENT1) such as S-(4-nitrobenzyl)-6-thioinosine and dipyridamole in a concentration-dependent manner. | Ribavirin | solute carrier family 29 member 1 (Augustine blood group) | Homo sapiens |
| 3 | On the other hand, Na+-dependence of ribavirin uptake was not observed, suggesting the involvement of ENT1, but not Na+-dependent concentrative nucleoside transporters, in ribavirin uptake in K562 cells. | Ribavirin | solute carrier family 29 member 1 (Augustine blood group) | Homo sapiens |
| 4 | These results suggest that ribavirin uptake into K562 cells is mainly mediated by ENT1, which may have a pivotal role in anticancer effect of ribavirin. | Ribavirin | solute carrier family 29 member 1 (Augustine blood group) | Homo sapiens |
| 5 | These results suggest that ribavirin uptake into K562 cells is mainly mediated by ENT1, which may have a pivotal role in anticancer effect of ribavirin. | Ribavirin | solute carrier family 29 member 1 (Augustine blood group) | Homo sapiens |