Title : Overexpression of ABCB1 and ABCG2 contributes to reduced efficacy of the PI3K/mTOR inhibitor samotolisib (LY3023414) in cancer cell lines.

Pub. Date : 2020 Oct

PMID : 32634436






6 Functional Relationships(s)
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1 Overexpression of ABCB1 and ABCG2 contributes to reduced efficacy of the PI3K/mTOR inhibitor samotolisib (LY3023414) in cancer cell lines. LY3023414 mechanistic target of rapamycin kinase Homo sapiens
2 Overexpression of ABCB1 and ABCG2 contributes to reduced efficacy of the PI3K/mTOR inhibitor samotolisib (LY3023414) in cancer cell lines. LY3023414 mechanistic target of rapamycin kinase Homo sapiens
3 LY3023414 (samotolisib) is a promising new dual inhibitor of phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR). LY3023414 mechanistic target of rapamycin kinase Homo sapiens
4 LY3023414 (samotolisib) is a promising new dual inhibitor of phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR). LY3023414 mechanistic target of rapamycin kinase Homo sapiens
5 LY3023414 (samotolisib) is a promising new dual inhibitor of phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR). LY3023414 mechanistic target of rapamycin kinase Homo sapiens
6 LY3023414 (samotolisib) is a promising new dual inhibitor of phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR). LY3023414 mechanistic target of rapamycin kinase Homo sapiens