Title : Azelastine a potent antihistamine agent, as hypolipidemic and modulator for aortic calcification in diabetic hyperlipidemic rats model.

Pub. Date : 2020 Jul 2

PMID : 32615812






2 Functional Relationships(s)
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1 10-DHGD showed comparatively lower effect.Conclusion: Anti-calcifying effect of azelastine might be related to upregulation of apo A (HDL-c) and downregulation of apo B mRNA expression indeed good modulator of aortic calcification.Impact Statement: Many studies have indicated that high-density lipoprotein-cholesterol (HDL-c) is inversely correlated with atherosclerotic plaque progression and could reduce cardiovascular disease risk. azelastine apolipoprotein B Rattus norvegicus
2 Our findings showed that azelastine ameliorated aortic calcification and increased apoA expression along with a decline in apo B. azelastine apolipoprotein B Rattus norvegicus