Title : Mechanism of Action of OnabotulinumtoxinA in Chronic Migraine: A Narrative Review.

Pub. Date : 2020 Jul

PMID : 32602955






1 Functional Relationships(s)
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1 RESULTS: Following injection into tissues, onabotulinumtoxinA inhibits soluble N-ethylmaleimide-sensitive fusion attachment protein receptor (SNARE)-mediated vesicle trafficking by cleaving one of its essential proteins, soluble N-ethylmaleimide-sensitive fusion attachment protein (SNAP-25), which occurs in both motor and sensory nerves. Ethylmaleimide synaptosome associated protein 25 Homo sapiens