Pub. Date : 2020 Aug
PMID : 32598049
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Adjustment of azathioprine dose should be based on a lower 6-TGN target level to avoid leucopenia in NUDT15 intermediate metabolizers. | Azathioprine | nudix hydrolase 15 | Homo sapiens |
| 2 | AIM: To investigate the association between NUDT15 polymorphisms and time-to-leucopenia in paediatric patients with inflammatory bowel disease (IBD) receiving azathioprine and to determine the relationship between NUDT15 polymorphisms and 6-thioguanine nucleotide (6-TGN) levels. | Azathioprine | nudix hydrolase 15 | Homo sapiens |
| 3 | CONCLUSION: NUDT15 polymorphisms were associated with time-to-leucopenia during azathioprine treatment in Korean paediatric patients with IBD. | Azathioprine | nudix hydrolase 15 | Homo sapiens |