Title : Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency.

Pub. Date : 2020 Aug 3

PMID : 32597829






1 Functional Relationships(s)
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1 Consistently, Klotho supplementation ameliorated HS-induced augmentation of reduced renal blood flow (RBF) response to intra-arterial infusion of Ang II and the thromboxane A2 analog U46619, which activated RhoA in both groups of mice and were associated with the inhibition of BP elevation, suggesting that abnormal response of RBF to Ang II contributes to HS-induced BP elevation. 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ras homolog family member A Mus musculus