Title : Resveratrol Exerts Anti-Osteoarthritic Effect by Inhibiting TLR4/NF-κB Signaling Pathway via the TLR4/Akt/FoxO1 Axis in IL-1β-Stimulated SW1353 Cells.

Pub. Date : 2020

PMID : 32581510






2 Functional Relationships(s)
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1 Resveratrol Exerts Anti-Osteoarthritic Effect by Inhibiting TLR4/NF-kappaB Signaling Pathway via the TLR4/Akt/FoxO1 Axis in IL-1beta-Stimulated SW1353 Cells. Resveratrol interleukin 1 alpha Homo sapiens
2 Results: IL-1beta treatment increased the expression of TLR4/NF-kappaB and phosphorylation of PI3K/Akt and FoxO1, while additional resveratrol further upregulated the expression of PI3K/Akt and FoxO1 phosphorylation but downregulated TLR4 signals in SW1353 cells. Resveratrol interleukin 1 alpha Homo sapiens