Pub. Date : 1988
PMID : 3257733
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of human neutrophil elastase by polyguanylic acid and other synthetic RNA homopolymers. | Poly G | elastase, neutrophil expressed | Homo sapiens |
| 2 | Poly G inhibits elastin proteolysis even when subsequently added to mixtures of elastin and HNE that have first been preincubated together for 10 min. | Poly G | elastase, neutrophil expressed | Homo sapiens |
| 3 | Complex formation between HNE and poly G is dependent on ionic rather than covalent interactions, since it is blocked by 0.6 M NaCl but not by inactivation of the enzyme"s catalytic-site serine residue with diisopropylfluorophosphate. | Poly G | elastase, neutrophil expressed | Homo sapiens |