Title : Multifaceted deregulation of gene expression and protein synthesis with age.

Pub. Date : 2020 Jul 7

PMID : 32576685






1 Functional Relationships(s)
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1 At the translational level, we uncovered sustained down-regulation of a set of 5"-terminal oligopyrimidine (5"-TOP) transcripts encoding protein synthesis and ribosome biogenesis machinery and regulated by the mTOR pathway. oligopyrimidine mechanistic target of rapamycin kinase Mus musculus