Title : Dietary Magnesium Intake and Leukocyte Telomere Attrition in Adults: The Regulatory Role of Serum Tumor Necrosis Factor α.

Pub. Date : 2020

PMID : 32565730






4 Functional Relationships(s)
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1 Conversely, there was a positive relationship between dietary magnesium and serum tumor necrosis factor (TNF) alpha, with an interquarter difference of 3.79 pmol/mL (P for trend = 0.006). Magnesium tumor necrosis factor Homo sapiens
2 Multivariate regression analysis revealed that the odds ratios (ORs) for shorter LTL and higher serum TNFalpha increased with magnesium intake, and the ORs of the differences between extreme quartiles were 2.60 (95% confidence interval (CI): 1.31-5.36; P = 0.003) and 1.98 (95% CI: 1.09-3.59; P = 0.008). Magnesium tumor necrosis factor Homo sapiens
3 There was a direct negative effect of dietary magnesium intake on LTL (B = -0.002; P = 0.001), which appeared to be indirectly influenced by TNFalpha (-0.002 to -0.0005). Magnesium tumor necrosis factor Homo sapiens
4 Conclusions: Dietary magnesium intake may be a critical component of the cellular aging process, and its effect could be partly mediated by TNFalpha. Magnesium tumor necrosis factor Homo sapiens