Title : Rab11 is essential for lgl mediated JNK-Dpp signaling in dorsal closure and epithelial morphogenesis in Drosophila.

Pub. Date : 2020 Aug 15

PMID : 32562757






4 Functional Relationships(s)
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1 Rab11 is essential for lgl mediated JNK-Dpp signaling in dorsal closure and epithelial morphogenesis in Drosophila. dipalmitoylphosphatidylserine basket Drosophila melanogaster
2 The JNK-Dpp signaling in the dorsolateral epidermis, plays an instrumental role in guiding their fate during this process. dipalmitoylphosphatidylserine basket Drosophila melanogaster
3 Here we show a probable mechanism via which lgl, a conserved tumour suppressor gene, regulates the JNK-Dpp pathway during dorsal closure and epithelial morphogenesis. dipalmitoylphosphatidylserine basket Drosophila melanogaster
4 Our experiment suggests Rab11 to be interacting with lgl as they seem to synergize in order to regulate the core JNK-Dpp signaling pathway during dorsal closure and also during adult thorax closure process. dipalmitoylphosphatidylserine basket Drosophila melanogaster