Pub. Date : 2020 Aug
PMID : 32544868
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 2"-fucosyllactose inhibits imiquimod-induced psoriasis in mice by regulating Th17 cell response via the STAT3 signaling pathway. | Imiquimod | signal transducer and activator of transcription 3 | Mus musculus |
| 2 | Furthermore, we have demonstrated that 2"-FL reduced the phosphorylation of STAT3 in the skin tissue from mice with IMQ stimulation, which could account for the decreasing recruitment of Th17 cells. | Imiquimod | signal transducer and activator of transcription 3 | Mus musculus |
| 3 | Our results indicate that 2"-FL ameliorates IMQ-induced psoriasis by inhibiting Th17 cell immune response and Th17-related cytokine secretion via modulation of the STAT3 signaling pathway. | Imiquimod | signal transducer and activator of transcription 3 | Mus musculus |