Title : Baicalin alleviates TNBS-induced colitis by inhibiting PI3K/AKT pathway activation.

Pub. Date : 2020 Jul

PMID : 32537016






2 Functional Relationships(s)
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1 Baicalin alleviates TNBS-induced colitis by inhibiting PI3K/AKT pathway activation. Trinitrobenzenesulfonic Acid AKT serine/threonine kinase 1 Homo sapiens
2 In the present study, the results revealed that baicalin not only significantly alleviated TNBS-induced colitis by reducing the release of IL-6, TNF-alpha and IL-1beta and increasing the level of IL-10, but promoted the expression of tight-junction proteins ZO-1 and beta-catenin, which may have been achieved by blockage of the PI3K/AKT signaling pathway. Trinitrobenzenesulfonic Acid AKT serine/threonine kinase 1 Homo sapiens