Pub. Date : 2020 Jul
PMID : 32537016
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Baicalin alleviates TNBS-induced colitis by inhibiting PI3K/AKT pathway activation. | Trinitrobenzenesulfonic Acid | AKT serine/threonine kinase 1 | Homo sapiens |
2 | In the present study, the results revealed that baicalin not only significantly alleviated TNBS-induced colitis by reducing the release of IL-6, TNF-alpha and IL-1beta and increasing the level of IL-10, but promoted the expression of tight-junction proteins ZO-1 and beta-catenin, which may have been achieved by blockage of the PI3K/AKT signaling pathway. | Trinitrobenzenesulfonic Acid | AKT serine/threonine kinase 1 | Homo sapiens |