Pub. Date : 2020 Jul
PMID : 32537016
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study, the results revealed that baicalin not only significantly alleviated TNBS-induced colitis by reducing the release of IL-6, TNF-alpha and IL-1beta and increasing the level of IL-10, but promoted the expression of tight-junction proteins ZO-1 and beta-catenin, which may have been achieved by blockage of the PI3K/AKT signaling pathway. | baicalin | interleukin 6 | Homo sapiens |
| 2 | In vitro, the results demonstrated that baicalin clearly inhibited the release of TNF-alpha, IL-6 and IL-1beta and promoted the expression of IL-10 in LPS-induced HT-29 cells, and significantly decreased LPS-induced HT-29 cell apoptosis by blockage of the PI3K/AKT signaling pathway. | baicalin | interleukin 6 | Homo sapiens |