Title : Metformin, an AMPK Activator, Inhibits Activation of FLSs but Promotes HAPLN1 Secretion.

Pub. Date : 2020 Jun 12

PMID : 32518807






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 After metformin treatment, expression of interleukin 6 (IL-6), TNF-alpha, and IL-1beta were significantly downregulated in RA-FLSs; however, increased expression of p-AMPK-alpha1, protein kinase A (PKA)-alpha1, and HAPLN1 (hyaluronan and proteoglycan link protein 1) was observed. Metformin interleukin 6 Homo sapiens
2 After metformin treatment, expression of interleukin 6 (IL-6), TNF-alpha, and IL-1beta were significantly downregulated in RA-FLSs; however, increased expression of p-AMPK-alpha1, protein kinase A (PKA)-alpha1, and HAPLN1 (hyaluronan and proteoglycan link protein 1) was observed. Metformin interleukin 6 Homo sapiens