Pub. Date : 2020 Sep 10
PMID : 32515841
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Degeneracy of the antithrombin binding sequence in heparin: 2-O-sulfated Iduronic acid can replace the critical glucuronic acid. | Glucuronic Acid | serpin family C member 1 | Homo sapiens |
| 2 | Heparin binds to and activates antithrombin (AT) through a specific pentasaccharide sequence in which a trisaccharide subsite, containing glucuronic acid (GlcA), has been considered as the initiator in the recognition of the polysaccharide by the protein. | Glucuronic Acid | serpin family C member 1 | Homo sapiens |
| 3 | Heparin binds to and activates antithrombin (AT) through a specific pentasaccharide sequence in which a trisaccharide subsite, containing glucuronic acid (GlcA), has been considered as the initiator in the recognition of the polysaccharide by the protein. | Glucuronic Acid | serpin family C member 1 | Homo sapiens |
| 4 | Indeed, a heparin octasaccharidic sequence obtained by chemoenzymatic synthesis, in which GlcA is replaced by IdoA2S has been found to similarly bind to and activate antithrombin. | Glucuronic Acid | serpin family C member 1 | Homo sapiens |