Title : [Interferon-regulating activity of the CelAgrip drug and its influence on the formation of reactive oxygen species and expression of innate immunity genes in Burkitt's lymphome cells cultures.]

Pub. Date : 2020

PMID : 32515564






1 Functional Relationships(s)
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1 CONCLUSION: In Namalva cells that do not produce EBV antigens the treatment of CA results in suppression of ROS generation and activation of the expression of genes ISG15 and P53 (TP53); in P3HR-1 cells producing EBV antigens, the opposite picture is observed - the formation of ROS and the expression of the IFN-alpha and IFN-lambda genes are activated and the activity of the ISG15 and P53 (TP53) genes is suppressed. Reactive Oxygen Species tumor protein p53 Homo sapiens