Pub. Date : 2020 Jun
PMID : 32508052
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | RNA-seq analysis identified p53 activation and other signatures accompanying this transdifferentiation; however, the p53 stabilizer nutlin-3 induced alphaSMA expression through reactive oxygen species generation but not through the p53 transcription/mitochondria-dependent pathway, whereas the p38 inhibitor SB203580 could partially inhibit alphaSMA expression. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
2 | RNA-seq analysis identified p53 activation and other signatures accompanying this transdifferentiation; however, the p53 stabilizer nutlin-3 induced alphaSMA expression through reactive oxygen species generation but not through the p53 transcription/mitochondria-dependent pathway, whereas the p38 inhibitor SB203580 could partially inhibit alphaSMA expression. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |