Pub. Date : 2020 Aug
PMID : 32502496
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The pivotal role of SUMO-1-JNK-Tau axis in an in vitro model of oxidative stress counteracted by the protective effect of curcumin. | Curcumin | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | Curcumin, a natural compound with anti-oxidant and anti-inflammatory effects, demonstrated to tackle oxidative stress re-equilibrating SUMO-1, JNK and Tau functions. | Curcumin | mitogen-activated protein kinase 8 | Homo sapiens |
| 3 | These results highlight the SUMO-1-JNK-Tau axis key role in oxidative stress and the protective effect of curcumin against this pathological event, focusing on the importance of SUMO/deSUMOylation balance to regulate essential cellular processes. | Curcumin | mitogen-activated protein kinase 8 | Homo sapiens |