Title : Discovery of Novel Indole-Based Allosteric Highly Potent ATX Inhibitors with Great In Vivo Efficacy in a Mouse Lung Fibrosis Model.

Pub. Date : 2020 Jul 9

PMID : 32479084






4 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Autotaxin (ATX) is the dominant catalytic enzyme accounting for the lipid mediator lysophosphatidic acid (LPA) through hydrolysis of lysophosphatidylcholine (LPC). lysophosphatidic acid ectonucleotide pyrophosphatase/phosphodiesterase 2 Mus musculus
2 Autotaxin (ATX) is the dominant catalytic enzyme accounting for the lipid mediator lysophosphatidic acid (LPA) through hydrolysis of lysophosphatidylcholine (LPC). lysophosphatidic acid ectonucleotide pyrophosphatase/phosphodiesterase 2 Mus musculus
3 Autotaxin (ATX) is the dominant catalytic enzyme accounting for the lipid mediator lysophosphatidic acid (LPA) through hydrolysis of lysophosphatidylcholine (LPC). lysophosphatidic acid ectonucleotide pyrophosphatase/phosphodiesterase 2 Mus musculus
4 Autotaxin (ATX) is the dominant catalytic enzyme accounting for the lipid mediator lysophosphatidic acid (LPA) through hydrolysis of lysophosphatidylcholine (LPC). lysophosphatidic acid ectonucleotide pyrophosphatase/phosphodiesterase 2 Mus musculus