Pub. Date : 2020 Dec
PMID : 32476534
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Antagonizing effect of icaritin on apoptosis and injury of hippocampal neurocytes induced by amyloid beta via GR/BDNF signaling pathway. | icaritin | brain derived neurotrophic factor | Mus musculus |
| 2 | ICA at 20 micromol/L (ICA20) the most significantly increased the viability of HT22 cells and the expressions of GR and BDNF in HT22 cells. | icaritin | brain derived neurotrophic factor | Mus musculus |
| 3 | More importantly, shRNA-GR reversed the positive effects of ICA20 on AD.Conclusions: ICA protected hippocampal neurocytes against Abeta25-35 via GR/BDNF signaling pathway. | icaritin | brain derived neurotrophic factor | Mus musculus |