Title : TGF-β1-mediated repression of SLC7A11 drives vulnerability to GPX4 inhibition in hepatocellular carcinoma cells.

Pub. Date : 2020 May 29

PMID : 32471991






1 Functional Relationships(s)
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1 Furthermore, TGF-beta1 increased reactive oxygen species (ROS) levels in PLC/PRF/5 cells and enhanced tert-butyl hydroperoxide-induced ROS levels in Huh7 cells; these changes were reversed by xCT overexpression. tert-Butylhydroperoxide solute carrier family 7 member 11 Homo sapiens