Title : Isobutyrylshikonin has a potentially stronger cytotoxic effect in oral cancer cells than its analogue shikonin in vitro.

Pub. Date : 2020 Aug

PMID : 32470830






1 Functional Relationships(s)
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1 The induction of apoptosis by both isobutyrylshikonin and shikonin was accompanied by activation of caspase-8, -9, -3, and PARP, loss of mitochondrial trans-membrane potential, and release of cytochrome c from the mitochondria. shikonin poly(ADP-ribose) polymerase 1 Homo sapiens