Title : Pharmacokinetic Interaction between Metformin and Verapamil in Rats: Inhibition of the OCT2-Mediated Renal Excretion of Metformin by Verapamil.

Pub. Date : 2020 May 21

PMID : 32455555






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In case of metformin and verapamil, organic cation transporter (OCT) 1 and 2 primarily mediate metformin distribution to the liver and its elimination into urine, whereas cytochrome P450 is responsible for the hepatic metabolism of verapamil. Metformin solute carrier family 22 member 1 Homo sapiens
2 In case of metformin and verapamil, organic cation transporter (OCT) 1 and 2 primarily mediate metformin distribution to the liver and its elimination into urine, whereas cytochrome P450 is responsible for the hepatic metabolism of verapamil. Metformin solute carrier family 22 member 1 Homo sapiens