Title : Synthesis and in vitro evaluation of novel non-oximes for the reactivation of nerve agent inhibited human acetylcholinesterase.

Pub. Date : 2020 Aug 1

PMID : 32454005






2 Functional Relationships(s)
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1 Synthesis and in vitro evaluation of novel non-oximes for the reactivation of nerve agent inhibited human acetylcholinesterase. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Since several decades oximes have been used as part of treatment of nerve agent intoxication with the aim to restore the biological function of the enzyme acetylcholinesterase after its covalent inhibition by organophosphorus compounds such as pesticides and nerve agents. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens