Title : Blocking Connexin-43 mediated hemichannel activity protects against early tubular injury in experimental chronic kidney disease.

Pub. Date : 2020 May 25

PMID : 32450899






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Uncoupled hemichannels permit the release of adenosine triphosphate (ATP) in to the extracellular space ( [ATP]e), where ATP binds to the P2X7 purinoreceptor and activates the nucleotide-binding domain and leucine-rich repeat containing (NLR) protein-3 (NLRP3) inflammasome. Leucine NLR family pyrin domain containing 3 Homo sapiens