Pub. Date : 2021 Jul
PMID : 32448086
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ATP citrate lyase (ACLY) is an important enzyme that catalyzes the conversion of citrate to acetyl-CoA in normal cells, facilitating the de novo fatty acid synthesis. | Citric Acid | ATP citrate lyase | Homo sapiens |
| 2 | Since ACLY-mediated conversion of citrate to acetyl-CoA constitutes the basis for fatty acid synthesis, ACLY seems to be quite an unexplored and promising therapeutic target for anticancer drug design. | Citric Acid | ATP citrate lyase | Homo sapiens |