Title : Arecoline induces epithelial mesenchymal transition in HK2 cells by upregulating the ERK-mediated signaling pathway.

Pub. Date : 2020 Sep

PMID : 32441858






1 Functional Relationships(s)
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1 Western blot analysis showed that arecoline treatment caused a dose-dependent decrease in E-cadherin expression and dose-dependent increases in N-cadherin, vimentin, alpha-SMA, and collagen expression; reverse transcriptase-polymerase chain reaction analysis revealed dose-dependent increases in alpha-SMA and collagen mRNA. Arecoline vimentin Homo sapiens