Pub. Date : 2020 May
PMID : 32436415
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PTEN expression was decreased and key downstream molecules in the phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway were gradually activated following bleomycin treatment. | Bleomycin | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | CONCLUSIONS: Downregulation of PTEN mediates bleomycin-induced premature senescence in lung cancer cells by suppressing autophagy via the PI3K/Akt/mTOR pathway. | Bleomycin | AKT serine/threonine kinase 1 | Homo sapiens |