Pub. Date : 2020 May 14
PMID : 32423023
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The NLRP3 (nucleotide-binding domain, leucine-rich-repeat-containing family, pyrin domain-containing 3) inflammasome senses pathogen-associated molecular patterns (PAMPs) and danger-associated molecular patterns (DAMPs), and activates caspase-1, which provokes release of proinflammatory cytokines such as interleukin-1beta (IL-1beta) and IL-18 as well as pyroptosis to engage in innate immune defense. | Leucine | interleukin 1 alpha | Homo sapiens |