Pub. Date : 2020 May
PMID : 32421530
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In preterm newborns, we previously showed a lower placental mRNA expression of FOLR1 along with higher folate and lower vitamin B12 cord blood levels. | Folic Acid | folate receptor alpha | Homo sapiens |
| 2 | Thereby we aimed to explore FOLR1 methylation in placentas of preterm newborns and hypothesized an increased FOLR1 methylation associated with cord blood folates and vitamin B12 concentrations. | Folic Acid | folate receptor alpha | Homo sapiens |
| 3 | Thereby we aimed to explore FOLR1 methylation in placentas of preterm newborns and hypothesized an increased FOLR1 methylation associated with cord blood folates and vitamin B12 concentrations. | Folic Acid | folate receptor alpha | Homo sapiens |
| 4 | Preterm newborns presented higher folate and lower vitB12 concentrations in cord blood which correlated with increased placental FOLR1 methylation. | Folic Acid | folate receptor alpha | Homo sapiens |
| 5 | DISCUSSION: In preterm newborns, placental FOLR1 expression is regulated by epigenetic mechanisms and presumably by maternal concentrations of folate and vitamin B12. | Folic Acid | folate receptor alpha | Homo sapiens |