Title : Effect of Cytochrome P450 and ABCB1 Polymorphisms on Imatinib Pharmacokinetics After Single-Dose Administration to Healthy Subjects.

Pub. Date : 2020 Jul

PMID : 32415468






2 Functional Relationships(s)
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1 Effect of Cytochrome P450 and ABCB1 Polymorphisms on Imatinib Pharmacokinetics After Single-Dose Administration to Healthy Subjects. Imatinib Mesylate ATP binding cassette subfamily B member 1 Homo sapiens
2 OBJECTIVE: To investigate whether polymorphisms in genes encoding cytochrome P450 (CYP) enzymes and ABCB1 transporter affect imatinib pharmacokinetic parameters. Imatinib Mesylate ATP binding cassette subfamily B member 1 Homo sapiens