Pub. Date : 2020
PMID : 32410998
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Paeoniflorin Resists H2O2-Induced Oxidative Stress in Melanocytes by JNK/Nrf2/HO-1 Pathway. | Hydrogen Peroxide | heme oxygenase 1 | Homo sapiens |
| 2 | Furthermore, PF activated c-Jun amino terminal kinase (JNK) and the nuclear factor E2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) pathway to counteract H2O2-induced oxidative damage in PIG1 and PIG3V. | Hydrogen Peroxide | heme oxygenase 1 | Homo sapiens |
| 3 | Furthermore, PF activated c-Jun amino terminal kinase (JNK) and the nuclear factor E2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) pathway to counteract H2O2-induced oxidative damage in PIG1 and PIG3V. | Hydrogen Peroxide | heme oxygenase 1 | Homo sapiens |
| 4 | Taken together, our study firstly demonstrates that PF resists H2O2-induced oxidative stress in melanocytes probably by activating JNK/Nrf2/HO-1 signaling, suggesting a potential therapeutic application of PF on vitiligo. | Hydrogen Peroxide | heme oxygenase 1 | Homo sapiens |