Title : Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.

Pub. Date : 2020 Jan-Dec

PMID : 32406319






3 Functional Relationships(s)
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1 Furthermore, we illustrated that desloratadine downregulated the expression of N-cadherin, Vimentin, Snail1, and Snail2, while upregulated the expression of E-cadherin in EJ and SW780 cells in vitro. desloratadine cadherin 1 Homo sapiens
2 The level of interleukin 6 was reduced in desloratadine-treated cells, while upregulation of interleukin 6 significantly abolished the anticancer activity of desloratadine in cell invasion and Bcl-2, Bax, Beclin1, LC3-I/II, N-cadherin, and E-cadherin expression in EJ cells. desloratadine cadherin 1 Homo sapiens
3 The level of interleukin 6 was reduced in desloratadine-treated cells, while upregulation of interleukin 6 significantly abolished the anticancer activity of desloratadine in cell invasion and Bcl-2, Bax, Beclin1, LC3-I/II, N-cadherin, and E-cadherin expression in EJ cells. desloratadine cadherin 1 Homo sapiens